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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR5A2
All Species:
22.12
Human Site:
Y235
Identified Species:
37.44
UniProt:
O00482
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00482
NP_003813.1
541
61331
Y235
A
A
L
P
P
T
D
Y
D
R
S
P
F
V
T
Chimpanzee
Pan troglodytes
XP_520248
771
84677
G469
L
A
A
G
P
P
A
G
P
L
G
D
F
G
A
Rhesus Macaque
Macaca mulatta
XP_001110281
541
61327
Y235
A
A
L
P
P
T
D
Y
D
R
S
P
F
V
T
Dog
Lupus familis
XP_547371
548
62005
Y242
A
A
L
P
P
T
D
Y
D
R
S
P
F
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P45448
560
64002
Y254
V
A
L
P
P
T
D
Y
D
R
S
P
F
V
T
Rat
Rattus norvegicus
Q9QWM1
560
63886
Y254
V
A
L
P
P
T
D
Y
D
R
S
P
F
V
T
Wallaby
Macropus eugenll
Q95L87
463
51850
K193
A
F
P
G
R
A
I
K
S
E
Y
P
E
P
Y
Platypus
Ornith. anatinus
XP_001505652
637
72367
Y331
T
A
L
P
P
T
D
Y
D
R
S
P
F
V
T
Chicken
Gallus gallus
O42101
501
57084
H223
Q
G
Y
Q
T
Y
G
H
F
P
S
R
A
I
K
Frog
Xenopus laevis
P70033
435
49986
R166
L
N
G
F
S
S
L
R
D
Q
Y
L
G
T
P
Zebra Danio
Brachydanio rerio
Q9PU65
477
54037
A208
Q
Y
I
G
N
A
M
A
Q
H
Y
Q
F
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P33244
1027
108400
T723
N
S
S
T
G
N
G
T
S
G
G
G
G
G
N
Honey Bee
Apis mellifera
XP_001122182
878
92065
Q579
Q
A
G
S
G
A
G
Q
H
Q
L
I
A
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791919
487
54933
I216
P
Y
G
P
P
P
Q
I
Q
P
L
N
Y
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
99.6
88.1
N.A.
86.9
86.9
57.4
80.6
90
23.6
27.5
N.A.
26.1
28.2
N.A.
45.4
Protein Similarity:
100
52.1
99.8
89.7
N.A.
90.3
90.5
67.8
83
91.1
41.2
44.7
N.A.
35.8
40.2
N.A.
61
P-Site Identity:
100
20
100
100
N.A.
93.3
93.3
13.3
93.3
6.6
6.6
6.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
13.3
93.3
20
20
20
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
58
8
0
0
22
8
8
0
0
0
0
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
43
0
50
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
8
0
8
0
0
0
0
8
0
0
0
58
0
0
% F
% Gly:
0
8
22
22
15
0
22
8
0
8
15
8
15
15
0
% G
% His:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
8
0
0
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
15
0
43
0
0
0
8
0
0
8
15
8
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
8
8
0
0
0
0
0
8
0
0
8
% N
% Pro:
8
0
8
50
58
15
0
0
8
15
0
50
0
15
15
% P
% Gln:
22
0
0
8
0
0
8
8
15
15
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
8
0
43
0
8
0
0
0
% R
% Ser:
0
8
8
8
8
8
0
0
15
0
50
0
0
0
8
% S
% Thr:
8
0
0
8
8
43
0
8
0
0
0
0
0
15
50
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
8
0
0
8
0
43
0
0
22
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _